Author Archive

USP <467> System Suitability…Where did my Carbon Tetrachloride go?

Achieving the sensitivity requirements for the Class 1 solvents in the revised USP can be, let’s face it, just plain difficult. By far, the biggest troublemaker is carbon tetrachloride in Procedure A. Sometimes a signal to noise ratio (S/N) of merely 3 seems a bit out of reach. Lets consider the concept of S/N for […]