Archive for the ‘Detection Techniques’ Category

Cannabis Residual Solvents Using MS Detection – I’m Not Hungry but I’ll Eat My Words Anyway

After coming back from a huge lunch at the Bellefonte Wok, a favorite Restek lunch spot, I’m completely stuffed, but I have to eat my words from a previous blog. In this blog, I made the case against using MS detection for headspace analysis of residual solvents in cannabis concentrates due to interference between the […]

GC-API-MS for BDEs with N2 at BFR2016

OK Jack, enough of the acronyms; this isn’t a word puzzle… Recently I let ChromaBLOGraphy readers know of our work on using gas chromatography (GC) with atmospheric pressure ionization (API) – mass spectrometry (MS) for analysis of brominated diphenyl ethers (BDEs) employing nitrogen (N2) carrier gas, which was presented at BFR2016 (BFR standing for Brominated […]

Fast gas chromatographic residue analysis in animal feed using split injection and atmospheric pressure chemical ionization tandem mass spectrometry

In a recent ChromaBLOGraphy post I mentioned that we are doing a campaign on “shoot-and-dilute GC”, also known as split injection GC, at RAFA 2015. A paper just published by Tienstra, Portolés, Hernández, and Mol used split injection with APGC for pesticide and other residue analysis in animal feed to achieve many of the benefits we’ve been […]

High Source Temperatures and Meeting EPA Tuning Criteria

My first blog here at Restek was a demonstration of how increasing the source temperature could improve the raw response of 2,4-dinitrophenol while maintaining the relative response. Four years later I’m here with the promised follow-up on the elevated source temperature effects on tune evaluations (and making adjustments via target tuning). This blog is going to deal […]

Which Source Configuration is Right for your Application?

If you have an Agilent 5973, 5975, or 5977 mass spec, there is a simple change to the configuration you can make to optimize its performance. By default, these systems come with a 3 mm drawout plate (or extraction lens) in their source assemblies. According to the manufacturer, this 3 mm lens is ideally suited for […]

Philae: Goodnight but Not Goodbye. Unlocking the Origins of Life: Comet 67P/Churyumov-Gerasimenko

On September 28th, 1969 a bright fireball exploded, shaking houses as it lit up the daytime sky outside of Murchison, Australia. Over the next forty-five years scientists have studied the Murchison Meteorite and found 14,000 compounds to include 92 different amino acids. Of the amino acids discovered, only 19 are found on earth. This rock, […]

Comet 67P/Churyumov-Gerasimenko: Data from Rosina.

While anxiously waiting for data from the COSAC (Cometary Sampling and Composition Experiment) aboard the Philae lander, we turn to some of the information that has already been sent by the Rosetta’s Rosina (Rosetta Orbiter Spectrometer for Ion and Neutral Analysis) instrument.  While sampling the comet’s coma they have found carbon dioxide in nearly the […]

Catching a Comet Traveling at 40,000 Miles per Hour

In 1993 the International Rosetta Mission was approved and over the next 21 years an estimated 1 billion Euros was invested in an audacious plan to catch a comet. On March 3rd, 2004 a European Ariane 5 rocket propelled the Rosetta on a ten year mission to orbit a comet.  While there have been 6 […]

Which GC instrument should I use for the analysis of pesticides in herbal tea? GC-MS/MS or GCxGC-TOFMS?

You may remember a while ago I posted a blog about the analysis of herbal tea using QuEChERS and GCxGC-TOFMS.   The LECO Pegasus GCxGC-TOFMS is a great instrument for analyzing complex samples because of the comprehensive chromatographic separation achieved (two columns with different selectivities).  The GCxGC-TOFMS also excels at non-target screening of compounds.  Lucky for […]

International Network of Environmental Forensics Conference – Cambridge, UK – The Invention of Mass Spectrometry and J.J. Thomson

I’m writing this post from St. John’s College at the University of Cambridge in the United Kingdom where I will be speaking at the International Network of Environmental Forensics Conference tomorrow on polychlorinated biphenyl (PCB) analysis with parallel dual-column comprehensive two-dimensional gas chromatography – time-of-flight mass spectrometry (2GCxGC-TOFMS).  I could wax on and on about […]