Archive for the ‘Method Translator and Flow Calculator’ Category

GC-API-MS for BDEs with N2 at BFR2016

OK Jack, enough of the acronyms; this isn’t a word puzzle… Recently I let ChromaBLOGraphy readers know of our work on using gas chromatography (GC) with atmospheric pressure ionization (API) – mass spectrometry (MS) for analysis of brominated diphenyl ethers (BDEs) employing nitrogen (N2) carrier gas, which was presented at BFR2016 (BFR standing for Brominated […]

Restek at BFR2016 in Toronto – APGC of Brominated Flame Retardants Using Helium and Nitrogen Carrier Gases

In only a few short weeks, I will be giving a presentation on the analysis of brominated flame retardants at BFR2016 in Toronto.  My colleagues and I used an atmospheric pressure ionization mass spectrometer with gas chromatography on an Rtx-1614  (15m x 0.25mm x 0.10µm) column to look at polybrominated diphenyl ethers (PBDEs) in various […]

Changing from helium to nitrogen carrier gas in gas chromatography while maintaining separation efficiency and analysis time

In two recent ChromaBLOGraphy posts (see links below) I described the experimental implementation of an idea Jaap de Zeeuw had to use nitrogen carrier gas for GC while maintaining the same separation efficiency and analysis time as what could be achieved by helium carrier gas. Wait, that’s impossible, right?!  Not if you go from a […]

New Restek EU PAH 15+1 Standard Separated on Rxi-PAH GC Column

Many of you may know that Restek recently developed and released a standard to support the determination of certain polycyclic aromatic hydrocarbons (PAHs) in food because they may be genotoxic and carcinogenic to humans.  You can find details on the EFSA Scientific Opinion that lists the so-called 15+1 PAHs here.  Hopefully you also know that […]

Restek’s EZGC Online Suite that includes the Method Translator and Flow Calculator, and a Chromatogram Modeler, wins a TASIA Award – Chris Nelson, One of the Suite Builders

The Analytical Scientist is a very smartly produced scientific magazine full of interesting articles, including many on chromatography.  I’ve had the pleasure of working with two of the minds behind this publication, Rich Whitworth and Frank van Geel, on a TAS GCxGC contribution, and have been impressed with the volume of quality work they’ve put […]

Peak Capacity in Capillary GC

Peak Capacity in capillary gas chromatography is different than sample loading capacity, which is something I’ve posted on multiple times recently in ChromaBLOGraphy.  Peak capacity is simply the number of theoretical peaks that can “fit” inside a chromatogram under some definition of how much they should be separated (e.g. baseline resolved or some other criterion).  […]

Alternate GC Carrier Gas: Helium to Nitrogen, 30m x 0.25mm x 0.25µm Column to 20m x 0.15mm x 0.15µm Column

I sent my earlier post, “Switching from Helium to Nitrogen Carrier Gas for GC by Switching from a 30m x 0.25mm x 0.25µm Column to a 20m x 0.15mm x 0.15µm Column” to Roy Lautamo at Restek West for review, as he has a critical eye for particulars.  He wanted to see finer detail in […]

Switching from Helium to Nitrogen Carrier Gas for GC by Switching from a 30m x 0.25mm x 0.25µm Column to a 20m x 0.15mm x 0.15µm Column

Our own Jaap de Zeeuw is a master chromatographer and he sometimes does his best work while sleeping.  Recently he was sharing with me an idea that woke him up in Singapore at 3 AM about switching from helium carrier gas for GC, which is still under threat from a supply shortage, to nitrogen, an […]

Does a different oven temperature programming rate change overload for PAHs on a GC column?

Jaap proposed that it might make a difference, so I wanted to test that possibility and add it to the following series on sample loading capacity, or “loadability” as Jaap calls it, for gas chromatography. Sample loading capacity for PAHs on a 30m x 0.25mm x 0.25µm Rxi-5ms GC column Does a thicker film GC column increase […]

Finally, some increased sample loading capacity for PAHs! Part 4: 30m x 0.32mm x 0.50µm Rxi-5ms

This may be the last post in my series on sample loading capacity for PAHs on Rxi-5ms GC columns. Sample loading capacity for PAHs on a 30m x 0.25mm x 0.25µm Rxi-5ms GC column Does a thicker film GC column increase sample loading capacity for PAHs? 30m x 0.25mm x 0.50µm Rxi-5ms Sample loading capacity […]