Archive for 2019

GC Inlet Liner Selection, Part I: Splitless Liner Selection

Splitless injections are used when detection of trace amounts of analytes is necessary and the goal is to recover close to 100% of all analytes that are injected into the instrument.  During a splitless injection, the split vent is closed for a predetermined amount of time, directing all inlet flow onto the column (with the […]

GC Inlet Liner Selection: An Introduction

GC inlet liners play an important role in GC sample introduction. The sample’s first contact is with the liner and from there it is transferred to the analytical column. In the case of liquid injections, the sample must be vaporized inside of the liner prior to transfer.  Choosing a proper inlet liner for your analysis […]

A Hoppy Little Story

Now that we’re getting into the warmer months of the year, you’re probably starting to see pop-up beer gardens or people outside relaxing with a nice cold one. Since the beer industry has been evolving and people are enjoying craft beers more and more, there are tons of unique brews on the market. If you […]

Are You Interested in Ultrashort-Chain PFAS Analysis? Be Sure to Screen Your Solvents/Solutions for Contamination

Trifluoroacetic acid (TFA) is the perfluorinated analogue of acetic acid with the shortest possible chain length (C2) among per- and polyfluoroalkyl substances (PFAS). Together with perfluorinated C3 compounds, they are defined as ultrashort-chain PFAS. C2 and C3 PFAS are ubiquitous and very mobile in global aquatic environment including rain, snow, river, and even ocean. TFA, […]

A Tale of Two Columns (CLPesticides and CLPesticides2)—Part IV: Fast 8081 Method Using GC Accelerator Kit

The moment has finally come to see how we can use the GC Accelerator to get the most horsepower for your 8081 analysis.  If you’ve been following this blog series, you will remember that in Part II, I talked about ways to make your runs faster.  I also showed you our previous fast “7 minute” […]

ASTM D 3606 17

Keep your benzene in check with ASTM D3606   While benzene historically has been used as an additive in gasoline and aviation fuel, it is a known toxic air pollutant and is regulated by both the EPA and European Union. While the ASTM has published both capillary and packed column methods this blog will focus […]

Take Care of Your LC System Investment and Minimize Downtime with Routine Maintenance!

For cannabis QA laboratories and producers, developing methods for HPLC analysis of cannabinoids can be time consuming and resource heavy.  While a lot of focus has been given to sample preparation and optimization of method conditions to maximize sample throughput, one VERY critical factor is often  overlooked: routine LC system maintenance. Keeping a log book […]

TO-15 + PAMS + TO-11A = China’s HJ759 + PAMS + HJ683 part 2: Deans switching and TO-15/PAMS

In a previous blog (TO-15 + PAMS + TO-11A = China’s HJ759 + PAMS + HJ683) Jason Herrington mentioned a dual column MS/FID setup for China’s combined HJ759 + PAMS + HJ683 method. While this could be done with a simple Y splitter (such as, a more elegant solution is to use a microfluidic […]

A Tale of Two Columns (CLPesticides and CLPesticides2)—Part III: Using the GC Accelerator Kit for Dual Column Analyses

In my previous two blogs (Part I and Part II), I mentioned the use of Restek’s GC Accelerator Oven Insert Kit (cat. #23849) for making your methods even faster.  The GC Accelerator kit was originally released with the intent of being used with an Agilent GC-MS system; however, this same kit can also be used […]

A Tale of Two Columns (CLPesticides and CLPesticides2)—Part II: Gaining Speed

In my previous blog post, I gave you a little history of the CLPesticides columns.  You’ll remember that I pointed out the 24 minute run times, which were promoted as being fast at the time.  Fortunately, there are ways to attain faster runs on this column pair for standard 8081 pesticides, due to their awesome […]