Archive for the ‘Cannabis’ Category

Pro EZGC Library Update: Cannabinoid Neutrals!

Every once in a while, I meet a customer who is interested in analyzing cannabinoids by GC. Before Pro EZGC, these requests were difficult since we could only guess on the resolution and conditions.  Through the power of Pro EZGC and some previously published blogs, I was able to come up with a column and […]

CBD Infused Beverages: The Recovery Dilemma

The Farm Bill of 2018 has opened a lot of doors in the cannabis industry. The effects are prominent in selection of cannabinoid containing products offered on the market. One such product that is gaining popularity in the industry are CBD infused drinks. These beverages present a unique challenge compared to other matrices because of […]

Tips on the analysis of pesticides and mycotoxins in cannabis products: Matrix matters! (Part III)

This is the final part of the blog series “Tips on the analysis of pesticides and mycotoxins in cannabis products: Matrix matters!” In Part I (here) and II (here), we covered various practical aspects related to matrix effects, spiking procedures, and recoveries. We gave real examples about how matrix type, matrix effects, and spiking strategies […]

Solid Phase Extraction: Separation is the Foundation of this Preparation!

In a previous post, we made the case that the foundation for analytical separations is sample preparation.  In this post, we would like to talk about how it works the other way around, too!  Separation can actually be the foundation for sample preparation.   In particular, we would like to talk about how solid phase extraction […]

Potency: Useful Techniques

The most labor-intensive part of determining the potency of samples containing cannabinoids is extraction. Due to a plethora of matrices, from candy, baked goods, lotions, and so on, selecting the most suitable extraction method can also be a challenge.  The following video and technical article will guide you through that initial process: How Potent is […]

The Foundation of Separation is Preparation

Restek is known as a leader in the field of chromatographic column technology.  The idea is built into our very identity – resolution technology is at the heart of Restek.  We also believe that proper sample preparation sets chromatography up for success, though, by reducing the incidence of confounding results and prolonging the lifetime of […]

Modifying QuEChERS for complicated matrices- High Sugar & Starch Samples

In previous blog posts for this series on QuEChERS, we discussed QuECHERS dSPE Selection, Modifying QuECHERS..-Dry Samples and Modifying QuEChERS..-High Fat Samples Once again, I suggest to use the following from the official QuEChERS website (, maintained by CVUA Stuttgart, these specific documents: For Extraction (Stage 1): For dSPE Cleanup (Stage 2): References […]

Modifying QuEChERS for complicated matrices- High Fat Samples

This post is part of a series on QuEChERS. Here are links to the previous two posts, in case you may wish to catch up before reading this one: QuEChERS dSPE selection-which one is best? Modifying QuECHERS for complicated matrices- Dry Samples (See Jana’s post here for further details on dry samples: QuECHERS approach optimization […]

Modifying QuEChERS for complicated matrices- Dry Samples

Before getting in to this discussion, I recommend reading my previous blog post first regarding classical applications for methods based on Quechers. QuEChERS methods were originally written to analyze pesticides in fruit and vegetable matrices, most of which have high water content and low fat content. More recently, the technique has been used for […]

Terpene Analysis Approaches – Part IV

We are back at it with another blog about terpene analysis! If you did not catch my previous post, be sure check it out here before moving on. Last time, I finished up by discussing how we would move away from analyzing terpenes in standards and dive into in-matrix analysis. Well…I lied. I’m sorry, but […]