Archive for the ‘QuEChERS’ Category

CBD Infused Beverages: The Recovery Dilemma

The Farm Bill of 2018 has opened a lot of doors in the cannabis industry. The effects are prominent in selection of cannabinoid containing products offered on the market. One such product that is gaining popularity in the industry are CBD infused drinks. These beverages present a unique challenge compared to other matrices because of […]

Solid Phase Extraction: Separation is the Foundation of this Preparation!

In a previous post, we made the case that the foundation for analytical separations is sample preparation.  In this post, we would like to talk about how it works the other way around, too!  Separation can actually be the foundation for sample preparation.   In particular, we would like to talk about how solid phase extraction […]

Modifying QuEChERS for complicated matrices- Soil and Sediment

In previous blog posts for this series on QuEChERS, we discussed QuECHERS dSPE Selection, Modifying QuECHERS..-Dry Samples, Modifying QuEChERS..-High Fat Samples, and Modifying QuEChERS..-High Sugar & Starch. Once again, I suggest using the following documents from the official QuEChERS website (QuEChERS.com), maintained by CVUA Stuttgart: For Extraction (Stage 1): https://www.QuEChERS.com/pdf/reality.pdf For dSPE Cleanup (Stage 2): […]

Not Every Matrix-Matched Calibration Is Made Equal – Case of Spinach

Matrix-matched calibrations are a popular option for complex matrices, such as food commodities. When it is employed, one can assume that the majority of matrix effects will be accounted for and there won’t be much difference between calibration standards and the tested samples. But are all matrix-matched calibrations equal? In the case of QuEChERS extraction, […]

The Foundation of Separation is Preparation

Restek is known as a leader in the field of chromatographic column technology.  The idea is built into our very identity – resolution technology is at the heart of Restek.  We also believe that proper sample preparation sets chromatography up for success, though, by reducing the incidence of confounding results and prolonging the lifetime of […]

How can analyte protectants and matrix help improve peak shapes?

In my last blog, I presented a new technique called low pressure gas chromatography (LPGC, Figure 1). Just to recap, the LPGC system consists of a relatively short analytical column (10 – 15 m) with large ID and thick film (e.g. 0.53 mm and 1.0 µm, respectively) which is restricted with a narrow guard column […]

Modifying QuEChERS for complicated matrices- High Sugar & Starch Samples

In previous blog posts for this series on QuEChERS, we discussed QuECHERS dSPE Selection, Modifying QuECHERS..-Dry Samples and Modifying QuEChERS..-High Fat Samples Once again, I suggest to use the following from the official QuEChERS website (QuEChERS.com), maintained by CVUA Stuttgart, these specific documents: For Extraction (Stage 1): https://www.QuEChERS.com/pdf/reality.pdf For dSPE Cleanup (Stage 2): https://www.QuEChERS.com/pdf/cleanup.pdf References […]

LPGC – Fast way to your pesticide analysis!

Throughput is one of the most important parameters in the lab. The more samples we can analyze in a day, the sooner we can get home. Enter Low Pressure GC (LPGC) – this is an invention from our brilliant Jaap de Zeeuw [1-2], where a relatively short analytical column (10 – 15 m) with large […]

Modifying QuEChERS for complicated matrices- High Fat Samples

This post is part of a series on QuEChERS. Here are links to the previous two posts, in case you may wish to catch up before reading this one: QuEChERS dSPE selection-which one is best? Modifying QuECHERS for complicated matrices- Dry Samples (See Jana’s post here for further details on dry samples: QuECHERS approach optimization […]

QuEChERS approach optimization for low-moisture matrices – case of honey and brown rice flour

Last month, Nancy published a blog summarizing how to approach samples with less than 80% water. Today, I want to go into more detail on how to deal with different commodities with less than 20%. As Nancy said, QuEChERS was first developed for high-moisture matrices such as strawberries and spinach. However, the method is very […]