In a recent ChromaBLOGraphy post I mentioned that we are doing a campaign on “shoot-and-dilute GC”, also known as split injection GC, at RAFA 2015. A paper just published by Tienstra, Portolés, Hernández, and Mol used split injection with APGC for pesticide and other residue analysis in animal feed to achieve many of the benefits we’ve been extolling for split injection with sensitive detectors.  Highlights from their paper were listed as:

Fast GC run time: < 10 min.  (JC note: fast cycle time too because of higher initial oven start temp)

Less matrix on the GC column and in the MS source.  (JC note: increased uptime)

Better compatibility with acetonitrile extracts (QuEChERS).  (JC note: most of solvent is split off before GC column)

Applicable to complex feed matrices.  (JC note: APGC with MS/MS is very sensitive and selective)

This entry was posted on Monday, November 2nd, 2015 at 2:16 pm and is filed under Conferences, Detection Techniques, Faster Analyses, Food, GC Injection Techniques, GC/MS, Optimizing Applications, Pesticides, Tips & Tricks. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site.